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Senior Scientist II- Biotherapeutics Oncology Drug Discovery

REQ-10056398
7月 03, 2025
USA

摘要

The Biotherapeutics group within Oncology Drug Discovery at Novartis Biomedical Research is seeking a highly motivated and collaborative Senior Scientist II to advance drug-conjugate discovery programs for the treatment of cancer patients. In this lab-based role, the successful candidate will apply cell and molecular biology techniques to deliver impactful data for target validation and drug optimization efforts. This role requires a strong understanding of and experience with in vitro cell-based assays for drug discovery. This individual will interact collaboratively with colleagues across Biomedical Research and will be a member of multidisciplinary project teams. This is a great opportunity to join a group dedicated to the discovery of biotherapeutics and to support advancement of drug discovery projects into the Novartis portfolio.

#LI-Onsite
This position will be located at Cambridge and will not have the ability to be located remotely

About the Role

Key Responsibilities:

  • Generates hypotheses to test, troubleshoots issues and designs and executes the next set of experiments with some input from senior lab members/manager.
  • Works independently and as a part of a team to design, execute, and analyze in vitro experiments to profile small molecules and biologics and elucidate mechanisms of action
  • Executes cell and molecular biology assays (e.g. cell titer glo, flow cytometry, JESS, western blot, MSD, HTRF)
  • Cultures cells using sterile technique including genetic engineering and validation of cell lines
  • Uses laboratory automation equipment (liquid handlers, plate readers, dispensers) to perform screens
  • Maintains an organized and detailed record of all experiments
  • Works collaboratively across teams and trains other members of team in areas of technical expertise as needed.
  • Clearly communicates findings and presents research to multidisciplinary project teams
  • Supports lab operations including management of materials, maintenance of instruments, and general lab duties

Role Requirements: 
Essential Requirements:

  • Bachelor's degree in biology or related field
  • Master's degree preferred
  • 5+ years of high-throughput screening experience
  • Industry experience preferred
  • Extensive experience with cellular assay development & execution, experience with high throughput screening workflows strongly preferred
  • Demonstrated ability to analyze, interpret and present data in a clear manner and use data to generate new hypotheses
  • Highly self-motivated, collaborative team player with exceptional organizational skills and curiosity to expand and diversify skillsets

Desired Requirements:

  • Understanding of drug discovery optimization processes
  • Experience with discovery of antibody-drug-conjugates

The salary for this position is expected to range between $93,800-$174,00/year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

To learn more about the culture, rewards and benefits we offer our people click here.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? http://www.novartis.com/about/strategy/people-and-culture

Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: http://talentnetwork.novartis.com/network

Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: http://www.novartis.com/careers/benefits-rewards

Biomedical Research
Universal Hierarchy Node
USA
Massachusetts
Cambridge (USA)
Research & Development
Full time
Regular
No
A female Novartis scientist wearing a white lab coat and glasses, smiles in front of laboratory equipment.
REQ-10056398

Senior Scientist II- Biotherapeutics Oncology Drug Discovery

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  1. http://www.novartis.com/sites/novartis_com/files/novartis-life-handbook.pdf
  2. http://www.novartis.com/about/strategy/people-and-culture
  3. http://talentnetwork.novartis.com/network
  4. http://www.novartis.com/careers/benefits-rewards
  5. mailto:[email protected]
  6. http://novartis.wd3.myworkdayjobs.com/en-US/Novartis_Careers/job/Cambridge-USA/Senior-Scientist-II--Biotherapeutics-Oncology-Drug-Discovery_REQ-10056398-1
  7. http://novartis.wd3.myworkdayjobs.com/en-US/Novartis_Careers/job/Cambridge-USA/Senior-Scientist-II--Biotherapeutics-Oncology-Drug-Discovery_REQ-10056398-1